Tottenham make three changes to the side which lost 4-0 to Newcastle two weeks ago. Destiny Udogie will miss the rest of the season after undergoing surgery on a thigh injury and Ben Davies replaces him. Pierre-Emile Hojbjerg and Dejan Kulusevski also come into the starting line-up. Richarlison is on the bench and could make his first appearance since 2 April after a knee injury.
Tottenham: Vicario, Davies, van de Ven, Romero, Porro, Bentancur, Hojbjerg, Werner, Maddison, Kulusevski, Son.
Substitutes: Austin, Dragusin, Bissouma, Richarlison, Gil, Royal, Lo Celso, Johnson, Sarr.
Arsenal are unchanged from the side which beat Chelsea 5-0 in midweek.
Arsenal: Raya, White, Saliba, Gabriel, Tomiyasu, Odegaard, Partey, Rice, Saka, Havertz, Trossard.
Substitutes: Ramsdale, Jesus, Smith Rowe, Martinelli, Nketiah, Kiwior, Jorginho, Vieira, Zinchenko.