Manchester United captain Bruno Fernandes returns from injury, replacing Rasmus Hojlund, which is the only change from their 1-0 defeat by Arsenal. Lisandro MartÃnez and Marcus Rashford are on the bench after injuries.
Manchester Utd: Onana, Dalot, Casemiro, Evans, Wan-Bissaka, Mainoo, Amrabat, Diallo, McTominay, Garnacho, Fernandes.
Substitutes: Bayindir, Martinez, Rashford, Eriksen, Hojlund, Antony, Kambwala, Forson, Collyer.
Kieran Trippier makes his first start for Newcastle since March after recovering from injury, replacing Tino Livramento as the only change from their 1-1 draw against Brighton. Alexander Isak, who came off unwell in that game, is fit to start. There is no Callum Wilson, who is absent due to illness.
Newcastle: Dubravka, Trippier, Krafth, Burn, Hall, Longstaff, Bruno Guimaraes, Anderson, J Murphy, Isak, Gordon.
Substiutes: Schar, Dummett, Joelinton, Ritchie, Barnes, Pope, Almiron, White, A Murphy.